
They’re the world’s most advanced models for coding and knowledge work—and their research capabilities offer an early glimpse of how AI models will contribute to scientific progress. Claude Fable 5.1 and Claude Mythos 5.1 are the same model, but with different levels of safeguards. Fable 5.1 is generally available, while Mythos 5.1 is available only through our trusted access programs; its safeguards are specifically designed to support work in cybersecurity and the life sciences. We tested the scientific research capabilities of Claude Fable 5.1 and Claude Mythos 5.1 across a wide range of domains.
We’re introducing Claude Fable 5.1 and Claude Mythos 5.1. They’re the world’s most advanced models for coding and knowledge work—and their research capabilities offer an early glimpse of how AI models will contribute to scientific progress.
Claude Fable 5.1 and Claude Mythos 5.1 are the same model, but with different levels of safeguards. Fable 5.1 is generally available, while Mythos 5.1 is available only through our trusted access programs; its safeguards are specifically designed to support work in cybersecurity and the life sciences.
Alongside its increased capabilities, Fable 5.1 takes important steps towards addressing the feedback we’ve received from customers on price, data retention, and safeguards.
Price . Fable 5.1 will cost an estimated 25% less than Fable 5 for typical workloads, wherever usage is billed by token. This is because we’re reducing our pricing on cache reads (where the model reads inputs that have already been processed and stored). For highly agentic work, the savings will often be much larger—up to approximately 45%.
We’re releasing this map under a Creative Commons license in advance of upcoming NASA VERITAS and ESA EnVision missions, in hopes that it might help them determine which geologic features to target for future observation.
As our models’ scientific capabilities improve, our investment in scientific progress is also growing. Last week, we previewed the Model Hardware Standard , which allows Claude to directly and safely operate laboratory equipment. We’ve also recently expanded our support for scientists through our AI for Science program , which provides free credits to researchers working on high-impact scientific projects, and we are offering steeply discounted usage through our new Claude Team plan for scientists .
Data retention . Our new system of Enterprise Frontier Safeguards (EFS) gives customers complete privacy (the same as a zero data retention policy) while still being state-of-the-art at preventing adversarial use. EFS works by storing data in cloud infrastructure controlled entirely by the customer, not Anthropic. It will be made available to enterprise customers in phases, beginning later this fall. Until EFS is available, eligible customers will be able to use Fable 5.1 with zero data retention.
Safeguards . We’ve improved our safeguards to reduce false positives (where the system flags benign content). In cybersecurity, our newest safeguards block 60% fewer false positives than before. In part, this is because Fable 5.1 can now be used to discover software vulnerabilities—though not to develop exploits for them. In biology, we’ve established an access program, developed in partnership with the US government, to enable access to Claude Mythos 5.1’s advanced biology capabilities. We expect to open enrollment for scientists soon.
Claude Fable 5.1 sets a new standard for coding, knowledge work, and long-running problem-solving tasks. The charts below show that Fable 5.1 is capable of much higher performance than its predecessor, Fable 5. And when set to Low or Medium effort, Fable 5.1 achieves results similar to or better than Fable 5’s at a much lower cost. (Note that Fable 5.1 defaults to High effort in Claude Code, and to Medium in Claude Cowork and on Claude.ai.)
They’re the world’s most advanced models for coding and knowledge work—and their research capabilities offer an early glimpse of how AI models will contribute to scientific progress Reported by Anthropic News on September 15, 2026.