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How GPT-5.6 Sol helps run quantum computing experiments

An MIT graduate student used OpenAI's GPT-5.6 Sol, connected via Codex to lab software, to autonomously run quantum computing experiments and calibrate superconducting qubits. The AI agent handled routine measurement workflows, identified transition frequencies, and calibrated control pulses, saving researchers significant time. While the agent struggled with weak or noisy signals requiring human guidance, it allowed the team to automate standard chip characterizations.

According to OpenAI, Beatriz Yankelevich, a graduate student in MIT’s Engineering Quantum Systems Group, tested GPT-5.6 Sol harnessed to Codex to explore streamlining quantum experimental workflows. Studying superconducting qubits cooled inside dilution refrigerators, Yankelevich connected Codex to lab software to enable the AI to run measurements, analyze results, and determine next steps. GPT-5.6 Sol completed routine measurement workflows autonomously on an uncalibrated six-qubit chip, identifying transition frequencies, calibrating control and read pulses, and determining how long qubits retained quantum information. When signals were clear, Codex finished standard measurement sequences with minimal researcher intervention. However, GPT-5.6 Sol encountered difficulties when experimental signals were weak or noisy, taking longer to find parameters and occasionally needing guidance from an experienced researcher. EQuS now regularly uses agents for routine measurements, which take days to characterize per chip. The agents allow researchers to run measurements overnight or while working elsewhere, checking in via phone. For novel experiments, Yankelevich assigns Codex agents narrower goals and uses their ability to write, modify, and test new code. Yankelevich states that she has built infrastructure to guide agents through measurement, theory, and chip design, allowing her to deploy multiple agents simultaneously and focus on higher-level work like interpreting results, devising experiments, and planning next steps.

Why it matters

This application demonstrates how AI agents integrated with laboratory software can handle multi-step scientific workflows and hardware calibration, freeing human researchers to focus on higher-level analysis and design.

Topic dossiers OpenAI